Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015837 | 0.90 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL9052713 | 0.89 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7018065 | 0.89 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7011008 | 0.89 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7013870 | 0.87 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7013586 | 0.87 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| Hydrochloric Acid SCHEMBL7015780 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7015339 | 0.82 | KMT2A (0.68) | SMN1; SMN2LMNAL3MBTL1TP53MEN1 | |
| SCHEMBL7013210 | 0.82 | MEN1 (0.53) | LMNATP53MEN1KMT2AMAOA | |
| SCHEMBL7011396 | 0.82 | ALDH1A1 (0.63) | SMN1; SMN2ALDH1A1PKMHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9095485-A | — | — | None | — | — | JP | disclosed |
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| JP-H0995485-A | HETEROCYCLIC COMPOUND, ITS PRODUCTION AND AGENT CONTAINING THE SAME | TAKEDA CHEM IND LTD | 1997-04-08 | — | — | JP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |