Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015837 | 0.88 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7016121 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL9052713 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7013870 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7012279 | 0.83 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7011008 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7020967 | 0.81 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7010770 | 0.80 | MEN1 (0.47) | SMN1; SMN2ALDH1A1PKMHTTMEN1 | |
| Hydrochloric Acid SCHEMBL7015780 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1PKMHTTLMNA | |
| SCHEMBL7016471 | 0.80 | TGM2 (0.40) | SMN1; SMN2ALDH1A1PKMHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |