Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016121 | 0.89 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2PKMHTTLMNA | |
| SCHEMBL7015464 | 0.84 | KMT2A (0.60) | SMN1; SMN2HTTLMNAMEN1KMT2A | |
| SCHEMBL7015837 | 0.82 | SMN1; SMN2 (0.70) | ALDH1A1SMN1; SMN2PKMHTTLMNA | |
| SCHEMBL7015237 | 0.82 | MEN1 (0.45) | ALDH1A1SMN1; SMN2PKMHTTLMNA | |
| SCHEMBL9052713 | 0.81 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2PKMHTTLMNA | |
| SCHEMBL7011008 | 0.81 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2PKMHTTLMNA | |
| SCHEMBL7013586 | 0.79 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2PKMHTTLMNA | |
| SCHEMBL7013870 | 0.79 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2PKMHTTLMNA | |
| SCHEMBL7016710 | 0.78 | MAOA (0.44) | ALDH1A1HTTLMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7015780 | 0.77 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2PKMHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |