Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202076 | 0.86 | LMNA (0.38) | CNR1CNR2KDM4EKMT2ALMNA | |
| SCHEMBL10433195 | 0.86 | STAT3 (0.50) | STAT3CNR1CNR2ADRB2KDM4E | |
| SCHEMBL10914967 | 0.79 | ADRB2 (0.53) | STAT3ADRB2KCNH2TOP2ATOP2B | |
| SCHEMBL7016264 | 0.79 | KDM4E (0.51) | STAT3CNR1CNR2KDM4EKMT2A | |
| SCHEMBL8204201 | 0.79 | CNR1 (0.36) | STAT3CNR1CNR2ADRB2KDM4E | |
| SCHEMBL10432848 | 0.79 | LMNA (0.51) | KDM4EKMT2ALMNAHPGDALDH1A1 | |
| SCHEMBL8911920 | 0.78 | LMNA (0.33) | CNR1CNR2KDM4EKMT2ALMNA | |
| SCHEMBL7817401 | 0.77 | ADRB2 (0.47) | STAT3ADRB2ALDH1A1KCNH2TOP2A | |
| SCHEMBL8913187 | 0.77 | CNR1 (0.31) | CNR1CNR2 | |
| SCHEMBL10433059 | 0.76 | STAT3 (0.48) | STAT3CNR1CNR2ADRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770083-B1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 2000-08-30 | — | — | EP | disclosed |