Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020671 | 0.83 | SMN1; SMN2 (0.49) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL30716729 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL17198268 | 0.80 | MEN1 (0.55) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL3018141 | 0.80 | ALDH1A1 (0.60) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL7016473 | 0.79 | KMT2A (0.46) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL31503950 | 0.78 | KMT2A (0.60) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL1446574 | 0.78 | KMT2A (0.60) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL20796131 | 0.77 | MEN1 (0.74) | MEN1KMT2AMAPTGAALMNA | |
| SCHEMBL3933135 | 0.76 | GAA (0.55) | MEN1KMT2AMAPTGAALMNA | |
| Hydrochloric Acid SCHEMBL3117154 | 0.76 | KMT2A (0.58) | MEN1KMT2AMAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317433-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020495-A2 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |
| EP-1087963-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | Chiron Corporation (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065897-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |