Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.56 |
| ▸ | GABRD | O14764 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.56 |
| ▸ | GABRE | P78334 | 1/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13697478 | 0.78 | KMT2A (0.78) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5225161 | 0.77 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5226233 | 0.75 | GABRP (0.74) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7011557 | 0.72 | GABRA1 (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10148327 | 0.69 | OGG1 (0.71) | RAB9AKMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL6008674 | 0.69 | CHRNA7 (0.57) | — | |
| Hydrochloric Acid SCHEMBL6006980 | 0.69 | CHRNA7 (0.56) | — | |
| SCHEMBL3505235 | 0.68 | KMT2A (0.69) | MAOBMEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL8155035 | 0.68 | KMT2A (0.78) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12377091 | 0.68 | KMT2A (0.78) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285671-B1 | PYRIDINE DERIVATIVES | ASAHI CHEMICAL IND (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0285671-A1 | PYRIDINE DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 1988-10-12 | — | — | EP | disclosed |