Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.53 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.51 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021606 | 0.89 | EPHX1 (0.52) | MAPTLMNAKMT2AEPHX1ALDH1A1 | |
| SCHEMBL7018465 | 0.87 | EGLN1 (0.59) | EGLN1SUCNR1MAPTKDM4EMEN1 | |
| SCHEMBL7016726 | 0.86 | SMN1; SMN2 (0.52) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL7019353 | 0.84 | MAPT (0.57) | EGLN1SUCNR1MAPTLMNAKMT2A | |
| SCHEMBL7018848 | 0.83 | LMNA (0.48) | SUCNR1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL7015908 | 0.83 | MAPK8 (0.47) | MAPTKDM4EMEN1KMT2AMAPK8 | |
| SCHEMBL4303922 | 0.82 | NCEH1 (0.54) | EGLN1NCEH1MEN1KMT2A | |
| SCHEMBL7012647 | 0.82 | EGLN1 (0.44) | EGLN1SUCNR1MAPTKDM4EMEN1 | |
| SCHEMBL7011724 | 0.81 | MEN1 (0.51) | KDM4EMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL7020816 | 0.80 | HSP90AA1 (0.63) | EGLN1MAPTKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155017-B1 | [1,8] NAPHTHYRIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | SHIRE BIOCHEM INC (CA) | 2003-01-15 | — | — | EP | claimed |