Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PANK1 | Q8TE04 | 1/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | STAMBP | O95630 | 1/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019353 | 0.88 | MAPT (0.57) | EGLN1SMN1; SMN2SUCNR1LMNAHPGD | |
| SCHEMBL7017409 | 0.87 | EGLN1 (0.53) | EGLN1KDM4ESUCNR1LMNAALDH1A1 | |
| SCHEMBL7014974 | 0.84 | MAPT (0.49) | RXFP1KDM4ESMN1; SMN2SUCNR1LMNA | |
| SCHEMBL7014015 | 0.83 | PTPN1 (0.47) | EGLN1KDM4ESMN1; SMN2SUCNR1LMNA | |
| SCHEMBL7014947 | 0.82 | EGLN1 (0.64) | EGLN1RXFP1KDM4ESMN1; SMN2SUCNR1 | |
| SCHEMBL7021606 | 0.81 | EPHX1 (0.52) | LMNAALDH1A1FAAHMAPK1STAMBP | |
| SCHEMBL7011724 | 0.81 | MEN1 (0.51) | KDM4ESMN1; SMN2LMNAHPGDTSHR | |
| SCHEMBL7016726 | 0.78 | SMN1; SMN2 (0.52) | KDM4ESMN1; SMN2LMNAHPGDTSHR | |
| SCHEMBL7019228 | 0.78 | ROCK2 (0.48) | KDM4ESMN1; SMN2LMNAHPGDALDH1A1 | |
| SCHEMBL7018848 | 0.75 | LMNA (0.48) | KDM4ESUCNR1LMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155017-B1 | [1,8] NAPHTHYRIDINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | SHIRE BIOCHEM INC (CA) | 2003-01-15 | — | — | EP | claimed |