Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760902 | 0.80 | HTT (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7499590 | 0.79 | GABRA1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7468895 | 0.78 | P4HTM (0.55) | P4HTMLMNA | |
| SCHEMBL12304432 | 0.78 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23286878 | 0.77 | GABRA1 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1808424 | 0.77 | GABRP (0.31) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2334583 | 0.77 | GABRA5 (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1404488 | 0.77 | GABRA1 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL575044 | 0.77 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21874280 | 0.77 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |
| EP-0139090-B1 | PROCESS FOR THE PRE-TREATMENT OF POLYIMIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | disclosed |
| US-4517254-A | ALKALI METAL HYDROXIDE, AMINOALKYLPOLYACID COMPOUNT | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-14 | — | — | US | disclosed |
| EP-0139090-A1 | Process for the pre-treatment of polyimides | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-02 | — | — | EP | disclosed |
| US-4248632-A | ACTIVATION OF A POLYMER SURFACE WITH A PALLADIUM COMPLEX SALT | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |