SCHEMBL1404488

SCHEMBL1404488

O=C(O)Cc1cnc(Cl)nc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.52
GABRA5 P31644 3/20 0.52
GABRB2 P47870 3/20 0.52
GABRA4 P48169 3/20 0.52
GABRP O00591 2/20 0.52
GABRD O14764 2/20 0.52
GABRB1 P18505 2/20 0.52
GABRG2 P18507 2/20 0.52
GABRB3 P28472 2/20 0.52
GABRA3 P34903 2/20 0.52
GABRA2 P47869 2/20 0.52
GABRE P78334 2/20 0.52
GABRA6 Q16445 2/20 0.52
GABRG1 Q8N1C3 2/20 0.52
GABRG3 Q99928 2/20 0.52
GABRQ Q9UN88 2/20 0.52
P4HTM Q9NXG6 2/20 0.52
AKR1B1 P15121 2/20 0.44
NAPRT Q6XQN6 1/20 0.44
CA2 P00918 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2724216 0.80 ALDH1A1 (0.41) GABRA1GABRA5GABRB2GABRA4GABRP
SCHEMBL23374479 0.80 CA2 (0.43) GABRA1GABRA5GABRB2GABRA4GABRP
SCHEMBL7499590 0.79 GABRA1 (0.53) GABRA1GABRA5GABRB2GABRA4GABRP
SCHEMBL25219823 0.78 P4HTM (0.55) P4HTM
SCHEMBL2334583 0.77 GABRA5 (0.62) GABRA1GABRA5GABRB2GABRA4GABRP
SCHEMBL23286878 0.77 GABRA1 (0.52) GABRA1GABRA5GABRB2GABRA4GABRP
SCHEMBL7017455 0.77 GABRP (0.52) GABRA1GABRA5GABRB2GABRA4GABRP
SCHEMBL256024 0.77 GABRP (0.61) GABRA1GABRA5GABRB2GABRA4GABRP
SCHEMBL30154481 0.77 GABRP (0.61) GABRA1GABRA5GABRB2GABRA4GABRP
SCHEMBL21702330 0.75 ALDH1A1 (0.55) GAAALDH1A1LMNANFKB1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700369-A Preparation method of 2- (2-chloropyrimidine-5-yl) acetic acid/ester 上海彩迩文生化科技有限公司 2024-03-15 CN claimed
EP-1920073-A2 METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS Dako Denmark A/S (DK) 2008-05-14 EP claimed
WO-2007031874-A2 METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS DAKO DENMARK A/S (US) 2007-03-22 WO claimed
WO-2024167927-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF REVERIE LABS, INC. (US) 2024-08-15 WO disclosed
CN-117700369-A Preparation method of 2- (2-chloropyrimidine-5-yl) acetic acid/ester 上海彩迩文生化科技有限公司 2024-03-15 CN disclosed
CN-117700369-A Preparation method of 2- (2-chloropyrimidine-5-yl) acetic acid/ester 上海彩迩文生化科技有限公司 2024-03-15 CN disclosed
CN-117700369-A Preparation method of 2- (2-chloropyrimidine-5-yl) acetic acid/ester 上海彩迩文生化科技有限公司 2024-03-15 CN disclosed
WO-2024012461-A1 METHYLTRANSFERASE INHIBITOR AND USE THEREOF 上海赛岚生物科技有限公司 2024-01-18 WO disclosed
WO-2023134629-A1 NUCLEAR TRANSPORT REGULATOR AND USE THEREOF 上海海雁医药科技有限公司 2023-07-20 WO disclosed
CN-109232541-B Prolyl hydroxylase and histone deacetylase dual inhibitor and preparation method and application thereof 中国医学科学院放射医学研究所 2020-04-24 CN disclosed
US-10036066-B2 In situ hybridization detection method DAKO DENMARK A/S (DK) 2018-07-31 US disclosed
WO-2007045998-A2 NEW NUCLEIC ACID BASE PAIRS DAKO DENMARK A/S (US) 2007-04-26 WO disclosed
WO-2007045998-A2 NEW NUCLEIC ACID BASE PAIRS DAKO DENMARK A/S (US) 2007-04-26 WO disclosed
WO-2007031874-A2 METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS DAKO DENMARK A/S (US) 2007-03-22 WO disclosed
WO-2007026252-A2 IN SITU HYBRIDIZATION DETECTION METHOD DAKO DENMARK A/S (US) 2007-03-08 WO disclosed
WO-2007026252-A2 IN SITU HYBRIDIZATION DETECTION METHOD DAKO DENMARK A/S (US) 2007-03-08 WO disclosed
WO-2007023390-A2 IMMUNOHISTOCHEMISTRY DETECTION METHOD DAKO DENMARK A/S (US) 2007-03-01 WO disclosed
WO-2007023390-A2 IMMUNOHISTOCHEMISTRY DETECTION METHOD DAKO DENMARK A/S (US) 2007-03-01 WO disclosed
WO-2007015168-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES DAKO DENMARK A/S (US) 2007-02-08 WO disclosed
WO-2007015168-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES DAKO DENMARK A/S (US) 2007-02-08 WO disclosed