Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017261 | 0.71 | MAPK1 (0.49) | MAPTGAANPC1RAB9AHTT | |
| SCHEMBL22146281 | 0.69 | ALDH1A1 (0.46) | ERCC5FEN1ELANEEGLN1TGM2 | |
| SCHEMBL13833647 | 0.69 | LMNA (0.49) | ERCC5FEN1ELANEMAPTGAA | |
| SCHEMBL19700242 | 0.67 | MAPT (0.39) | TGM2MAPTGAANPC1RECQL | |
| SCHEMBL7011912 | 0.67 | ELANE (0.46) | ELANE | |
| SCHEMBL15474256 | 0.65 | ERCC5 (0.72) | ERCC5FEN1 | |
| SCHEMBL11869898 | 0.64 | MAPT (0.42) | CTDSP1MAPTGAARAB9AHTT | |
| SCHEMBL7010620 | 0.63 | SMN1; SMN2 (0.49) | ELANEMAPTGAANPC1RAB9A | |
| SCHEMBL16428215 | 0.63 | ELANE (0.42) | ERCC5FEN1ELANEEGLN1CTDSP1 | |
| SCHEMBL13764544 | 0.63 | ALDH1A1 (0.57) | ELANEEGLN1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836602-B1 | FUNGICIDAL PYRIMIDINONES | DU PONT (US) | 2002-01-30 | — | — | EP | claimed |
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |