Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462849 | 0.89 | CNR1 (0.47) | ALDH1A1KMT2AKDM4EPOLBCNR1 | |
| SCHEMBL8638685 | 0.86 | KDM4E (0.38) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL4773904 | 0.81 | CA12 (0.43) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL7755595 | 0.77 | KDM5A (0.48) | KDM5AKDM5BALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3463544 | 0.76 | CA12 (0.44) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL6297418 | 0.74 | CNR2 (0.38) | KMT2AKDM4ELMNAMEN1 | |
| SCHEMBL4770346 | 0.73 | CPB2 (0.33) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL4773772 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL28200636 | 0.72 | ALDH1A1 (0.39) | ALDH1A1KMT2ACA12CA1CA2 | |
| Acetic Acid SCHEMBL30329984 | 0.71 | KDM5A (0.37) | KDM5AKDM5BALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309565-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012199-A1 | HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-02-14 | — | — | WO | disclosed |