Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011724 | 0.90 | MEN1 (0.51) | KDM4EPOLBMEN1KMT2ANPC1 | |
| SCHEMBL7020859 | 0.84 | MEN1 (0.57) | ROCK2ROCK1MAPTTP53KDM4E | |
| SCHEMBL7014974 | 0.82 | MAPT (0.49) | MAPTTP53KDM4EL3MBTL1POLB | |
| SCHEMBL7020453 | 0.82 | MTNR1A (0.53) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL7020699 | 0.81 | TAS1R3 (0.52) | KDM4EPOLBMEN1KMT2ANPC1 | |
| SCHEMBL7014015 | 0.80 | PTPN1 (0.47) | MAPTTP53KDM4EL3MBTL1POLB | |
| SCHEMBL7018848 | 0.79 | LMNA (0.48) | TP53KDM4EADORA2AADORA1MEN1 | |
| SCHEMBL7015908 | 0.79 | MAPK8 (0.47) | MAPTKDM4EADORA2AADORA1MEN1 | |
| SCHEMBL7017460 | 0.79 | EPHX2 (0.48) | ADORA2AADORA1 | |
| SCHEMBL7018465 | 0.78 | EGLN1 (0.59) | MAPTKDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086106-B1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |