Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | SPR | P35270 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342883 | 0.93 | ACHE (0.75) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL31277254 | 0.93 | ACHE (0.75) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL7023429 | 0.84 | TRPV1 (0.77) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL14074033 | 0.84 | SNCA (0.72) | MEN1NPC1RAB9AKMT2AHPGD | |
| SCHEMBL28412156 | 0.83 | PTGS1 (0.77) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL10071693 | 0.81 | TYR (0.81) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL25217961 | 0.81 | TRPV1 (0.67) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL20182262 | 0.81 | TRPV1 (0.73) | ACHETRPV1PTGS1PTGS2KMT2A | |
| SCHEMBL15145405 | 0.80 | PTGS1 (0.81) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL7024455 | 0.80 | HTR1A (0.61) | ACHETRPV1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |