Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | SPR | P35270 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | IDO1 | P14902 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31277254 | 1.00 | ACHE (0.75) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL7019674 | 0.93 | ACHE (0.66) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL28412156 | 0.90 | PTGS1 (0.77) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL10071693 | 0.89 | TYR (0.81) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL25217961 | 0.88 | TRPV1 (0.67) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL20182262 | 0.88 | TRPV1 (0.73) | ACHETRPV1PTGS1PTGS2KMT2A | |
| SCHEMBL15145405 | 0.87 | PTGS1 (0.81) | ACHETRPV1PTGS1PTGS2MEN1 | |
| SCHEMBL5341652 | 0.86 | MEN1 (0.73) | TRPV1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5343192 | 0.86 | KMT2A (0.73) | ACHETRPV1MEN1NPC1RAB9A | |
| SCHEMBL794173 | 0.86 | TYR (0.70) | ACHETRPV1PTGS1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174510-A1 | N-acetylserotonin Derivatives as TrkB Activators and Uses Thereof | EMORY UNIVERSITY | 2023-06-08 | — | — | US | disclosed |
| US-20230174510-A1 | N-acetylserotonin Derivatives as TrkB Activators and Uses Thereof | EMORY UNIVERSITY | 2023-06-08 | — | — | US | disclosed |
| EP-4142714-A1 | N-ACETYLSEROTONIN DERIVATIVES AS TRKB ACTIVATORS AND USES THEREOF | Emory University (US) | 2023-03-08 | — | — | EP | disclosed |
| US-20130196050-A1 | SALTY TASTE ENHANCER | AJINOMOTO CO., INC. (JP) | 2013-08-01 | — | — | US | disclosed |
| US-7183318-B2 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2007-02-27 | — | — | US | disclosed |
| US-7126012-B2 | Substituted cyclic compounds | LES LABORATOIRES SERVIER (FR) | 2006-10-24 | — | — | US | disclosed |
| US-7115752-B2 | Substituted cyclic compounds | LES LABORATOIRES SERVIER (FR) | 2006-10-03 | — | — | US | disclosed |
| US-20050124682-A1 | Substituted cyclic compounds | LESIEUR DANIEL (FR) | 2005-06-09 | — | — | US | disclosed |
| US-6872851-B1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | LES LABORATORIES SERVIER (FR) | 2005-03-29 | — | — | US | disclosed |
| US-20050059729-A1 | Substituted cyclic compounds | LESIEUR DANIEL (FR) | 2005-03-17 | — | — | US | disclosed |
| US-20040002490-A1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | LESIEUR DANIEL (FR) | 2004-01-01 | — | — | US | disclosed |
| US-20040002491-A1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | LESIEUR DANIEL (FR) | 2004-01-01 | — | — | US | disclosed |
| US-6605632-B1 | Affinity for melatonin receptors | LES LABORATOIRES SERVIER (FR) | 2003-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196050-A1 | SALTY TASTE ENHANCER | TAS2R10, TAS2R5, TAS1R1 | ACHE 1300/4885TRPV1 458/4885PTGS1 1229/4885 |
| US-20230174510-A1 | N-acetylserotonin Derivatives as TrkB Activators and Uses Thereof | BDNF, NTRK2, NGF | ACHE 545/4885TRPV1 190/4885PTGS1 2650/4885 |
| US-20050059729-A1 | Substituted cyclic compounds | CCNY, CCNT2, TECR | ACHE 1165/4885TRPV1 2763/4885PTGS1 1712/4885 |
| US-20040002491-A1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | CYP4B1, CYP3A5, MC2R | ACHE 1880/4885TRPV1 2408/4885PTGS1 616/4885 |
| US-20050124682-A1 | Substituted cyclic compounds | CCNY, CCNT2, TECR | ACHE 1165/4885TRPV1 2763/4885PTGS1 1712/4885 |
| US-20040002490-A1 | Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them | CYP3A5, CYP4B1, MC2R | ACHE 1899/4885TRPV1 2372/4885PTGS1 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.