Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.81 |
| ▸ | SPR | P35270 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | IDO1 | P14902 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794173 | 0.90 | TYR (0.70) | TYRSPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL31277254 | 0.89 | ACHE (0.75) | TYRSPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL5342883 | 0.89 | ACHE (0.75) | TYRSPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL20182262 | 0.86 | TRPV1 (0.73) | TYRSPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL10071699 | 0.86 | PTGS1 (0.68) | TYRSPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL25217961 | 0.86 | TRPV1 (0.67) | TYRSPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL15145409 | 0.86 | PTGS1 (0.71) | TYRSPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL1960963 | 0.84 | SPR (0.78) | SPRKDM4EALDH1A1NPSR1CYP2D6 | |
| SCHEMBL803841 | 0.84 | PTGS1 (0.84) | TYRSPRKDM4EALDH1A1NPSR1 | |
| SCHEMBL803617 | 0.84 | PTGS1 (0.82) | TYRSPRKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295624-B2 | Amide derivative and whitening agent | AJINOMOTO CO., INC. (JP) | 2016-03-29 | — | — | US | disclosed |
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20130196050-A1 | SALTY TASTE ENHANCER | AJINOMOTO CO., INC. (JP) | 2013-08-01 | — | — | US | disclosed |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196050-A1 | SALTY TASTE ENHANCER | TAS2R10, TAS2R5, TAS1R1 | TYR 378/4885SPR 1218/4885KDM4E 1153/4885 |
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | TYR 3/4885SPR 3569/4885KDM4E 1343/4885 |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | TYR 3/4885SPR 3569/4885KDM4E 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.