Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.53 |
| ▸ | ARG2 | P78540 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275768 | 0.80 | KMT2A (0.52) | GRIK1GRIK2ARG2GSRCYP1A2 | |
| SCHEMBL11354511 | 0.78 | ALOX15 (0.42) | GRIK1GRIK2ALDH1A1ALOX15KMT2A | |
| SCHEMBL29950721 | 0.77 | GRIK1 (0.68) | GRIK1GRIK2GRIA1GRIA2SLC1A3 | |
| SCHEMBL4854891 | 0.77 | GRIK1 (0.68) | GRIK1GRIK2GRIA1GRIA2SLC1A3 | |
| SCHEMBL12064021 | 0.77 | GRIK1 (0.68) | GRIK1GRIK2GRIA1GRIA2SLC1A3 | |
| Hydrochloric Acid SCHEMBL11361480 | 0.77 | ALOX15 (0.41) | GRIK1GRIK2ALDH1A1ALOX15KMT2A | |
| SCHEMBL5369538 | 0.76 | ALDH1A1 (0.51) | CYP1A2ALDH1A1ALOX15BLMFNTA | |
| SCHEMBL18735918 | 0.75 | ALOX15 (0.41) | GRIK1GRIK2ALDH1A1ALOX15KMT2A | |
| SCHEMBL19800869 | 0.75 | BHMT (0.49) | GRIK1GRIK2GSRCYP1A2GRM8 | |
| SCHEMBL19800785 | 0.75 | BHMT (0.54) | GRIK1GRIK2NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| EP-1276712-A2 | 2,6-DIAMINO-6-METHYL-HEPTANOIC ACID AND DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | Degussa AG (DE) | 2003-01-22 | — | — | EP | disclosed |
| US-6504047-B2 | 2,6-diamino-6-methyl-heptanoic acid and derivatives as chemical intermediates useful for preperation of biological active compounds such as alpha-amino-epsilon caprolactam derivatives | DEGUSSA AG (DE) | 2003-01-07 | — | — | US | disclosed |
| US-20020016366-A1 | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof | DEGUSSA AG (DE) | 2002-02-07 | — | — | US | disclosed |
| WO-2001083423-A2 | 2,6-DIAMINO-6-METHYL-HEPTANOIC ACID AND DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF | DEGUSSA AG (DE) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016366-A1 | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof | CYP2D6, CYP2B6, CYP2A6 | GRIK1 656/4885GRIK2 1205/4885ARG2 3599/4885 |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | GRIK1 2914/4885GRIK2 3197/4885ARG2 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.