Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAP2K3 | P46734 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.33 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.33 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022252 | 0.84 | MEN1 (0.35) | MEN1KMT2AMAP2K3LCKBTK | |
| SCHEMBL1403852 | 0.78 | SIRT3 (0.46) | MEN1KMT2AMAP2K3LCKBTK | |
| SCHEMBL28309038 | 0.75 | SIRT3 (0.38) | MEN1KMT2AMAP2K3LCKBTK | |
| SCHEMBL30591940 | 0.75 | MAP2K3 (0.44) | MEN1KMT2AMAP2K3LCKBTK | |
| SCHEMBL19691158 | 0.75 | KMT2A (0.37) | MEN1KMT2AMAP2K3LCKBTK | |
| SCHEMBL3145246 | 0.75 | MAP2K3 (0.44) | MEN1KMT2AMAP2K3LCKBTK | |
| SCHEMBL22290211 | 0.73 | SIRT3 (0.38) | MEN1KMT2AMAP2K3LCKBTK | |
| SCHEMBL30205008 | 0.73 | SIRT3 (0.38) | MEN1KMT2AMAP2K3LCKBTK | |
| SCHEMBL31165155 | 0.72 | CTDSP1 (0.32) | — | |
| SCHEMBL22290178 | 0.71 | P2RX7 (0.34) | MEN1KMT2AMAP2K3LCKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368324-A1 | QUINAZOLINES AS MMP-13 INHIBITORS | Warner-Lambert Company LLC (US) | 2003-12-10 | — | — | EP | disclosed |
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
| WO-2002064572-A1 | QUINAZOLINES AS MMP-13 INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | MEN1 4715/4885KMT2A 3258/4885MAP2K3 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.