Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 3/20 | 0.49 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.38 |
| ▸ | CACNG1 | Q06432 | 3/20 | 0.38 |
| ▸ | CACNB2 | Q08289 | 3/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023218 | 0.80 | MMP1 (0.53) | MMP1FPR2PROKR1GPR119TACR3 | |
| SCHEMBL7018357 | 0.79 | MMP1 (0.49) | MMP1FPR2PROKR1GPR119TACR3 | |
| SCHEMBL6911913 | 0.79 | MMP1 (0.51) | MMP1FPR2PROKR1GPR119TACR3 | |
| SCHEMBL7017112 | 0.77 | MMP2 (0.42) | KMT2A | |
| SCHEMBL940600 | 0.75 | MMP1 (0.57) | MMP1FPR2PROKR1GPR119TACR3 | |
| SCHEMBL941502 | 0.75 | FPR2 (0.64) | MMP1FPR2PROKR1GPR119TACR3 | |
| SCHEMBL942134 | 0.75 | MMP1 (0.49) | MMP1FPR2PROKR1GPR119TACR3 | |
| SCHEMBL7143720 | 0.75 | MMP1 (0.51) | MMP1FPR2PROKR1GPR119CACNB4 | |
| SCHEMBL7021130 | 0.74 | MMP1 (0.52) | MMP1FPR2PROKR1GPR119CACNB4 | |
| SCHEMBL7011537 | 0.74 | MMP1 (0.52) | MMP1FPR2PROKR1GPR119CACNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370536-A1 | METALLOPROTEINASE INHIBITORS | AstraZeneca AB (SE) | 2003-12-17 | — | — | EP | disclosed |
| EP-1370556-A1 | METALLOPROTEINASE INHIBITORS | AstraZeneca AB (SE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002074767-A1 | METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | WO | disclosed |
| WO-2002074750-A1 | METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | WO | disclosed |