Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023218 | 0.84 | MMP1 (0.53) | MMP1FPR2PROKR1LIPETACR3 | |
| SCHEMBL7018357 | 0.82 | MMP1 (0.49) | MMP1FPR2PROKR1LIPETACR3 | |
| SCHEMBL6021557 | 0.80 | MMP1 (0.52) | MMP1FPR2PROKR1LIPEIP6K1 | |
| SCHEMBL7020098 | 0.79 | MMP1 (0.53) | MMP1FPR2PROKR1LIPETACR3 | |
| SCHEMBL943749 | 0.76 | MMP1 (0.56) | MMP1FPR2PROKR1LIPETACR3 | |
| SCHEMBL943397 | 0.75 | FPR2 (0.48) | MMP1FPR2PROKR1LIPEHRH3 | |
| SCHEMBL941398 | 0.74 | MMP1 (0.54) | MMP1FPR2PROKR1LIPEIP6K1 | |
| SCHEMBL942627 | 0.74 | FPR2 (0.47) | MMP1FPR2PROKR1KMT2AALDH1A1 | |
| SCHEMBL940600 | 0.73 | MMP1 (0.57) | MMP1FPR2PROKR1LIPETACR3 | |
| SCHEMBL941502 | 0.73 | FPR2 (0.64) | MMP1FPR2PROKR1TACR3TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | MMP9, MMP10, MMP3 | MMP1 17/4885FPR2 1510/4885PROKR1 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.