Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023919 | 0.91 | TPSAB1 (0.47) | TPSAB1GRIN2BCYP2D6CYP2C9 | |
| SCHEMBL7694668 | 0.91 | TPSAB1 (0.47) | TPSAB1GRIN2BCYP2D6CYP2C9 | |
| SCHEMBL7021064 | 0.85 | PRMT5 (0.46) | TPSAB1PARP1PRMT5 | |
| SCHEMBL8205180 | 0.84 | TPSAB1 (0.52) | TPSAB1GRIN2BCYP2D6CYP2C9 | |
| SCHEMBL7403728 | 0.80 | TPSAB1 (0.49) | TPSAB1 | |
| SCHEMBL7020168 | 0.79 | TPSAB1 (0.43) | TPSAB1 | |
| SCHEMBL7027708 | 0.78 | TPSAB1 (0.43) | TPSAB1 | |
| SCHEMBL7020326 | 0.78 | TPSAB1 (0.43) | TPSAB1 | |
| SCHEMBL7018545 | 0.78 | TPSAB1 (0.43) | TPSAB1 | |
| SCHEMBL7020466 | 0.78 | TPSAB1 (0.43) | TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |