Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357201 | 0.86 | ACHE (0.59) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL15894579 | 0.81 | SELL (0.59) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL69718 | 0.76 | ACHE (1.00) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL14625525 | 0.74 | ALDH1A1 (0.42) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL9499181 | 0.73 | ACHE (0.48) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL51957 | 0.71 | LMNA (0.75) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL50784 | 0.71 | LMNA (0.56) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL5612512 | 0.71 | ALDH1A1 (0.48) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL29612051 | 0.71 | ALDH1A1 (0.48) | ACHESELLSELPSELETRPA1 | |
| SCHEMBL4623974 | 0.71 | LMNA (0.56) | ACHESELLSELPSELETRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003533337-A | — | — | 2003-11-11 | — | — | JP | claimed |
| EP-1225978-A1 | HYDROFORMYLATION OF UNSATURATED COMPOUNDS USING POLYMERIC PHOSPHITE LIGANDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-07-31 | — | — | EP | claimed |
| WO-2001021308-A1 | HYDROFORMYLATION OF UNSATURATED COMPOUNDS USING POLYMERIC PHOSPHITE LIGANDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-03-29 | — | — | WO | claimed |