Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476941 | 0.95 | L3MBTL1 (0.51) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| SCHEMBL238962 | 0.85 | L3MBTL1 (0.62) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| 2,4'-Oxybis(Nitrobenzene) SCHEMBL9474586 | 0.84 | HSPB1 (0.62) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| SCHEMBL6750951 | 0.84 | L3MBTL1 (0.57) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| SCHEMBL1283885 | 0.84 | HSPB1 (0.67) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| SCHEMBL9393606 | 0.83 | ALDH1A1 (0.51) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| SCHEMBL9393603 | 0.83 | ALDH1A1 (0.51) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| SCHEMBL10944795 | 0.83 | L3MBTL1 (0.56) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| SCHEMBL2649297 | 0.83 | L3MBTL1 (0.70) | L3MBTL1HPGDLTA4HPTGS1PTGS2 | |
| SCHEMBL7123876 | 0.83 | L3MBTL1 (0.56) | L3MBTL1HPGDLTA4HPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230097678-A1 | NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2023-03-30 | — | — | US | disclosed |
| EP-4110776-A1 | NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2023-01-04 | — | — | EP | disclosed |
| CN-115151538-A | Macrocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-10-04 | — | — | CN | disclosed |
| CN-103242212-B | A kind of brain histamine H 3precursor of Receptor Radioligand and preparation method thereof | NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-11-04 | — | — | CN | disclosed |
| CN-103242212-A | Precursor of brain histamine H3 receptor radioligand and preparation method of precursor | UNIV NANJING SCIENCE & TECH | 2013-08-14 | — | — | CN | disclosed |
| CN-101874798-B | Difunctional inhibitor of leukotriene A4 hydrolase and cyclooxygenase and application thereof | UNIV BEIJING | 2012-08-29 | — | — | CN | disclosed |
| CN-101874798-A | Difunctional inhibitor of leukotriene A4 hydrolase and cyclooxygenase and application thereof | UNIV BEIJING | 2010-11-03 | — | — | CN | disclosed |
| CN-1127476-C | 2-phenoxyaniline derivs. | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-11-12 | — | — | CN | disclosed |
| EP-1031556-B1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6162832-A | 2-Phenoxyaniline derivatives | TAISHO PHARMACEUTICAL CO., INC. (JP) | 2000-12-19 | — | — | US | disclosed |
| CN-1276783-A | 2-Phenoxyaniline Derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2000-12-13 | — | — | CN | disclosed |
| EP-1031556-A1 | 2-PHENOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-08-30 | — | — | EP | disclosed |
| EP-0303415-B1 | Herbicidally active phenoxy-alkanecarboxylic acid derivatives | SUNTORY LTD (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5205855-A | Postemergence, preemergence herbicides | SUNTORY LIMITED (JP) | 1993-04-27 | — | — | US | disclosed |
| US-4976773-A | SELECTIVITY BETWEEN MONOCOYLEDON PLANTS | SUNTORY LIMITED (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0303415-A2 | Herbicidally active phenoxy-alkanecarboxylic acid derivatives | SUNTORY LIMITED (JP) | 1989-02-15 | — | — | EP | disclosed |
| US-4607051-A | Carbamic acid compound and use as a pesticide | HOFFMANN-LA ROCHE INC. (US) | 1986-08-19 | — | — | US | disclosed |
| US-4413010-A | Carbamic acid esters and use as pesticides | HOFFMANN-LA ROCHE INC. (US) | 1983-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230097678-A1 | NEW MACROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | C1S, C1R, F12 | L3MBTL1 4349/4885HPGD 3057/4885LTA4H 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.