Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.30 |
| ▸ | RARB | P10826 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028454 | 0.87 | HTR2A (0.35) | GPR84HTR2AHTR2C | |
| SCHEMBL7032286 | 0.87 | GPR84 (0.37) | KIF11GPR84MAOB | |
| SCHEMBL8041175 | 0.85 | CYP17A1 (0.39) | KIF11GPR84MAOBRARBRARA | |
| SCHEMBL8518012 | 0.85 | CYP17A1 (0.39) | KIF11GPR84MAOBRARBRARA | |
| SCHEMBL8518015 | 0.85 | CYP17A1 (0.39) | KIF11GPR84MAOBRARBRARA | |
| SCHEMBL7030006 | 0.84 | RARB (0.39) | KIF11GPR84HTR2AHTR2CMAOB | |
| SCHEMBL7021186 | 0.84 | GPR84 (0.35) | GPR84FFAR4 | |
| SCHEMBL9139450 | 0.82 | CYP17A1 (0.37) | KIF11GPR84MAOB | |
| SCHEMBL8518315 | 0.82 | GPR84 (0.36) | KIF11GPR84HTR2AMAOBFFAR4 | |
| SCHEMBL8518318 | 0.82 | GPR84 (0.36) | KIF11GPR84HTR2AMAOBFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |