Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 7/20 | 0.52 |
| ▸ | FLT1 | P17948 | 5/20 | 0.52 |
| ▸ | FLT4 | P35916 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219485 | 0.79 | NOTUM (0.56) | ALOX15TSHRCASP1NOTUMRAB9A | |
| SCHEMBL9365467 | 0.79 | HSD17B1 (0.51) | ALOX15TSHRCASP1NOTUMRAB9A | |
| SCHEMBL14112974 | 0.79 | NPC1 (0.54) | ALOX15TSHRCASP1NOTUMKDR | |
| SCHEMBL74359 | 0.76 | ALOX15 (0.96) | ALOX15TSHRCASP1NOTUMKDR | |
| SCHEMBL6291969 | 0.75 | TRPV1 (0.43) | ALOX15TSHRCASP1NOTUMNPC1 | |
| SCHEMBL10726923 | 0.74 | ALOX15 (1.00) | ALOX15TSHRCASP1NOTUMKDR | |
| SCHEMBL4777736 | 0.74 | ALOX15 (0.59) | ALOX15TSHRCASP1NOTUMKDR | |
| SCHEMBL344598 | 0.74 | ALOX15 (0.59) | ALOX15TSHRCASP1NOTUMKDR | |
| SCHEMBL16090371 | 0.74 | TSHR (0.59) | ALOX15TSHRCASP1NOTUMKDR | |
| SCHEMBL2854988 | 0.74 | RAB9A (0.59) | ALOX15TSHRCASP1NOTUMKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180070591-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180070591-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9820486-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2017-11-21 | — | — | US | disclosed |
| US-9820486-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2017-11-21 | — | — | US | disclosed |
| EP-2906640-B1 | COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, METHODS FOR MAKING AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING | PRC DESOTO INT INC (US) | 2017-11-15 | — | — | EP | disclosed |
| EP-2756043-B1 | COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING | PRC DESOTO INT INC (US) | 2017-04-12 | — | — | EP | disclosed |
| US-20160262396-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2016-09-15 | — | — | US | disclosed |
| US-9426995-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2016-08-30 | — | — | US | disclosed |
| US-9181628-B2 | Coating/sealant systems, aqueous resinous dispersions, and methods of electrocoating | PRC-DESOTO INTERNATIONAL, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| EP-2906640-A1 | COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, METHODS FOR MAKING AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING | PRC-Desoto International, Inc. (US) | 2015-08-19 | — | — | EP | disclosed |
| US-20080160452-A1 | Developer for light sensitive planographic printing plate material and manufacturing process of planographic printing plate employing the same | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-0749433-B1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | SYNGENTA LTD (GB) | 2003-05-07 | — | — | EP | disclosed |
| US-5952359-A | NEMATICIDES, INSECTICIDES AND MITICIDES; 1,1-DIFLUORO-3-(THIAZOLYL OR ISOTHIAZOYL-THIO (OR SULFINYL OR SULFONYL)-PROP-1-ENE DERIVATIVES | ZENECA LIMITED (GB) | 1999-09-14 | — | — | US | disclosed |
| US-5912243-A | NOVEL COMPOUNDS FOR CONTROLLING NEMATODES, INSECT OR ACARID PESTS | ZENECA LIMITED (GB) | 1999-06-15 | — | — | US | disclosed |
| US-5705516-A | NEMATOCIDES, INSECTICIDES, ACARICIDES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| EP-0749433-A1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024403-A1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1995-09-14 | — | — | WO | disclosed |
| EP-0241901-B1 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5061794-A | Effective against pseudomonads | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0241901-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180070591-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | ALOX15 589/4885TSHR 4109/4885CASP1 2000/4885 |
| US-20160262396-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | ALOX15 589/4885TSHR 4109/4885CASP1 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.