⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343990 | 0.79 | NOS2 (0.31) | — | |
| SCHEMBL17056242 | 0.75 | — | — | |
| SCHEMBL12653525 | 0.75 | — | — | |
| SCHEMBL30010705 | 0.73 | CA12 (0.32) | — | |
| SCHEMBL301858 | 0.72 | — | — | |
| SCHEMBL28838385 | 0.68 | LMNA (0.30) | — | |
| SCHEMBL9001480 | 0.65 | CA1 (0.31) | — | |
| SCHEMBL7019044 | 0.65 | MAOA (0.33) | — | |
| SCHEMBL7503453 | 0.65 | MAPT (0.45) | — | |
| SCHEMBL22767836 | 0.62 | CA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001345-B | Heterocyclic derivatives and use thereof | 株式会社C&C新药研究所 | 2021-03-02 | — | — | CN | disclosed |
| US-6670447-B2 | An 3-acyl-4-substituted-oxazolidin-2,5-dione that readily reacts with nucleophilic reagents such as free amino acids; use in peptide synthesis for example | MITSUI CHEMICALS, INC. (JP) | 2003-12-30 | — | — | US | disclosed |
| EP-1298127-A1 | AMINO ACID-N-CARBOXY ANHYDRIDES HVAING SUBSTITUENT AT NITROGEN | Mitsui Chemicals, Inc. (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20020173664-A1 | Amino acid-n-carboxy anhydrides hvaing substituent at nitrogen | MITSUI CHEMICALS, INC. (JP) | 2002-11-21 | — | — | US | disclosed |