Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229131 | 0.82 | MAOA (0.31) | MAOA | |
| SCHEMBL4743254 | 0.78 | APLNR (0.41) | — | |
| SCHEMBL7348348 | 0.70 | MAOA (0.37) | MAOAMAOB | |
| SCHEMBL6769741 | 0.69 | HTR6 (0.37) | MAOAMAOB | |
| SCHEMBL4775469 | 0.66 | MAPT (0.39) | MAOA | |
| SCHEMBL7022084 | 0.65 | — | — | |
| SCHEMBL19300150 | 0.64 | — | — | |
| SCHEMBL1099053 | 0.64 | — | — | |
| SCHEMBL1318768 | 0.64 | — | — | |
| SCHEMBL17174420 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326865-A2 | AZA- AND POLYAZA-NAPHTHALENYL CARBOXAMIDES USEFUL AS HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002030930-A2 | AZA- AND POLYAZA-NAPHTHALENYL CARBOXAMIDES USEFUL AS HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2002-04-18 | — | — | WO | disclosed |