SCHEMBL35366

SCHEMBL35366

C=CCOC(=O)NCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 9/20 0.38
ERN1 O75460 3/20 0.37
HRH4 Q9H3N8 2/20 0.36
HRH3 Q9Y5N1 2/20 0.36
BRD4 O60885 2/20 0.36
TSHR P16473 1/20 0.34
TGM2 P21980 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7023232 0.93 ERN1 (0.34) ACHEERN1HRH4HRH3BRD4
SCHEMBL1286118 0.88 ACHE (0.38) ACHEERN1HRH4HRH3BRD4
SCHEMBL7090002 0.84 BRD4 (0.42) ACHEERN1HRH4HRH3BRD4
SCHEMBL8763776 0.82 ACHE (0.46) ACHEHRH4HRH3TSHR
SCHEMBL35590 0.81 ACHE (0.33) ACHE
SCHEMBL3664836 0.81 ACHE (0.46) ACHE
SCHEMBL5916828 0.79 EPHX1 (0.50) ACHETSHR
SCHEMBL3676772 0.78 TGM2 (0.46) ACHEERN1TSHRTGM2
SCHEMBL307977 0.78 ZDHHC20 (0.51) TSHRTGM2
SCHEMBL8769203 0.77 ACHE (0.63) ACHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1833 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
US-11926689-B2 Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof ALCON INC. (CH) 2024-03-12 US claimed
US-20230364832-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES ALCON INC. (CH) 2023-11-16 US claimed
WO-2023209631-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230350100-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 US claimed
WO-2023209630-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
EP-3802080-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-07-19 EP claimed
EP-3969268-B1 METHOD FOR PRODUCING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2023-07-05 EP claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
EP-3802081-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-03-01 EP claimed
US-7247692-B2 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. (US) 2007-07-24 US claimed
WO-2006039467-A2 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-13 WO claimed
US-20060074208-A1 Biomedical devices containing amphiphilic block copolymers JOHNSON & JOHNSON VISION CARE, INC. 2006-04-06 US claimed
US-6759496-B2 POLYMERS OF POLY(2-OXAZOLINE) ENDCAPPED WITH A POLYMERIZABLE, ETHYLENICALLY UNSATURATED RADICAL BAUSCH & LOMB INCORPORATED 2004-07-06 US claimed
US-20020075448-A1 Poly(2-oxazoline) biomedical devices BAUSCH HEALTH US, LLC 2002-06-20 US claimed
EP-0611367-B1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB (US) 1997-06-25 EP claimed
US-5449729-A Vinyl monomer and crosslinking agent and acrylates with styrene BAUSCH & LOMB INCORPORATED (US) 1995-09-12 US claimed
EP-0611367-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. BAUSCH & LOMB (US) 1994-08-24 EP claimed
WO-1993009084-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO claimed
EP-0396364-A2 Novel vinyl carbonate and vinyl carbamate contact lens material monomers BAUSCH & LOMB INCORPORATED (US) 1990-11-07 EP claimed