Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 11/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021799 | 0.85 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7990698 | 0.85 | TPSAB1 (0.37) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020466 | 0.82 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7018545 | 0.82 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7029085 | 0.82 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7026286 | 0.78 | F2 (0.45) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7020182 | 0.78 | F2 (0.45) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7018692 | 0.78 | F2 (0.45) | F2PRSS1 | |
| SCHEMBL7016138 | 0.77 | TPSAB1 (0.41) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7025656 | 0.77 | PRMT5 (0.38) | TPSAB1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |