Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 12/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023796 | 0.85 | TPSAB1 (0.41) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7444854 | 0.75 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7025656 | 0.71 | PRMT5 (0.38) | TPSAB1ALDH1A1TSHR | |
| SCHEMBL7134370 | 0.69 | F2 (0.41) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7020466 | 0.68 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7029085 | 0.68 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7018545 | 0.68 | TPSAB1 (0.43) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7398979 | 0.66 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL7021757 | 0.65 | TPSAB1 (0.42) | TPSAB1F2F7F3PRSS1 | |
| SCHEMBL7021913 | 0.64 | F2 (0.42) | TPSAB1F2F7F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |