Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633370 | 0.80 | CYP19A1 (0.43) | CYP19A1KIF11ALDH1A1TSHRPNMT | |
| SCHEMBL3356661 | 0.79 | ALDH1A1 (0.50) | CYP19A1KIF11ALDH1A1TSHRPNMT | |
| SCHEMBL4463685 | 0.79 | CYP19A1 (0.46) | CYP19A1KIF11ALDH1A1TSHRPNMT | |
| SCHEMBL9332683 | 0.79 | CYP19A1 (0.46) | CYP19A1KIF11ALDH1A1TSHRPNMT | |
| SCHEMBL196785 | 0.79 | TSHR (0.50) | CYP19A1KIF11ALDH1A1TSHRPNMT | |
| SCHEMBL29048828 | 0.78 | KIF11 (0.49) | CYP19A1KIF11ALDH1A1TSHRPNMT | |
| SCHEMBL11300726 | 0.77 | CYP19A1 (0.53) | CYP19A1KIF11ALDH1A1TSHRPNMT | |
| SCHEMBL592796 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPK1MEN1CYP1A2 | |
| SCHEMBL8860094 | 0.77 | CYP19A1 (0.69) | CYP19A1KIF11ALDH1A1TSHRMAPK1 | |
| SCHEMBL8137247 | 0.77 | ESR1 (0.50) | CYP19A1KIF11ALDH1A1TSHRPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276461-A2 | PERSONAL CLEANSING BAR AND PREPARATION PROCESS | UNILEVER PLC (GB) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001080821-A2 | PERSONAL CLEANSING BAR AND PREPARATION PROCESS | UNILEVER PLC (GB) | 2001-11-01 | — | — | WO | disclosed |