Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028335 | 0.93 | CA2 (0.38) | FFAR4ESR2NPC1RAB9A | |
| SCHEMBL7026859 | 0.86 | ESR2 (0.33) | FFAR4ESR2NPC1RAB9ACYP3A4 | |
| SCHEMBL7027206 | 0.86 | PANK3 (0.34) | FFAR4ESR2RORC | |
| SCHEMBL7026094 | 0.86 | ESR2 (0.40) | FFAR4ESR2CYP3A4CYP2C9ESR1 | |
| SCHEMBL7029316 | 0.84 | ESR2 (0.40) | ESR2CYP3A4CYP2C9ESR1 | |
| SCHEMBL7021187 | 0.82 | KIF11 (0.36) | FFAR4KIF11 | |
| SCHEMBL8725535 | 0.81 | NAAA (0.35) | FFAR4CYP3A4CYP2C9 | |
| SCHEMBL7024343 | 0.81 | NAAA (0.35) | FFAR4CYP3A4CYP2C9 | |
| SCHEMBL8024745 | 0.81 | KDM1A (0.35) | NPC1RAB9AKIF11CYP3A4CYP2C9 | |
| SCHEMBL8382754 | 0.81 | KDM1A (0.35) | NPC1RAB9AKIF11CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |