Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.62 |
| ▸ | RARG | P13631 | 3/20 | 0.62 |
| ▸ | RARA | P10276 | 2/20 | 0.62 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878042 | 0.87 | RARA (0.51) | RARBRARGRARAWDR5ACLY | |
| SCHEMBL6871319 | 0.84 | RARA (0.47) | RARBRARGRARATNFRSF1AHTT | |
| SCHEMBL6879657 | 0.80 | RARA (0.44) | RARBRARGRARAWDR5TNFRSF1A | |
| SCHEMBL6878038 | 0.79 | KDM4E (0.49) | RARBRARGRARACA12CA1 | |
| SCHEMBL6878037 | 0.79 | KDM4E (0.49) | RARBRARGRARACA12CA1 | |
| SCHEMBL7024481 | 0.78 | RARA (0.58) | RARBRARGRARAWDR5IKBKE | |
| SCHEMBL31325762 | 0.78 | RARA (0.73) | RARBRARGRARAWDR5CA12 | |
| SCHEMBL1421835 | 0.78 | RARA (0.73) | RARBRARGRARAWDR5CA12 | |
| SCHEMBL6880780 | 0.77 | RARA (0.44) | RARBRARGRARAWDR5TNFRSF1A | |
| SCHEMBL6870705 | 0.77 | RARA (0.44) | RARBRARGRARATNFRSF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832081-B1 | BICYCLIC-AROMATIC COMPOUNDS | GALDERMA RECH DERMATOLOGIQUE (FR) | 2003-01-29 | — | — | EP | disclosed |
| EP-0832081-A1 | BICYCLIC-AROMATIC COMPOUNDS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997033881-A1 | BICYCLIC-AROMATIC COMPOUNDS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-09-18 | — | — | WO | disclosed |