Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026061 | 0.85 | ACHE (0.50) | ACHECHRM2CHRM1CHRM3TAAR1 | |
| SCHEMBL7018101 | 0.84 | L3MBTL1 (0.46) | ACHEL3MBTL1GLSPDK2PPARA | |
| SCHEMBL23420055 | 0.81 | L3MBTL1 (0.46) | L3MBTL1PDK2TAAR1 | |
| SCHEMBL7024522 | 0.81 | L3MBTL1 (0.44) | L3MBTL1GLSPDK2 | |
| SCHEMBL16993182 | 0.81 | L3MBTL1 (0.62) | L3MBTL1PDK2PPARAHDAC3HDAC1 | |
| SCHEMBL7027971 | 0.76 | F2 (0.48) | — | |
| SCHEMBL18739284 | 0.75 | CA14 (0.36) | L3MBTL1PDK2HDAC1HDAC2 | |
| SCHEMBL3010204 | 0.74 | DRD2 (0.49) | ACHE | |
| SCHEMBL31505912 | 0.74 | DRD2 (0.49) | ACHE | |
| SCHEMBL31541772 | 0.74 | L3MBTL1 (0.49) | L3MBTL1GLSPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |