Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23420055 | 0.88 | L3MBTL1 (0.46) | L3MBTL1PDK2RIPK1CTSBCTSS | |
| SCHEMBL7024522 | 0.85 | L3MBTL1 (0.44) | L3MBTL1GLSPDK2HTR2CSLC6A4 | |
| SCHEMBL16993182 | 0.84 | L3MBTL1 (0.62) | L3MBTL1PDK2HTR2CSLC6A4NPSR1 | |
| SCHEMBL7025868 | 0.84 | ACHE (0.48) | L3MBTL1GLSPDK2HDAC3HDAC1 | |
| SCHEMBL7017694 | 0.83 | MEN1 (0.42) | ALDH1A1LMNAHTT | |
| SCHEMBL7021352 | 0.83 | GLS (0.53) | GLSHTR2CSLC6A4AKT1RIPK1 | |
| SCHEMBL25829780 | 0.79 | L3MBTL1 (0.46) | L3MBTL1PDK2HTR2CSLC6A4AKT1 | |
| SCHEMBL2245966 | 0.79 | AKT1 (0.48) | L3MBTL1PDK2HTR2CSLC6A4AKT1 | |
| SCHEMBL31541772 | 0.78 | L3MBTL1 (0.49) | L3MBTL1GLSPDK2HTR2CSLC6A4 | |
| SCHEMBL18545548 | 0.77 | PDK2 (0.52) | L3MBTL1PDK2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6417203-B1 | HETEROCYCLIC AMIDES | PFIZER INC. | 2002-07-09 | — | — | US | disclosed |
| US-6180627-B1 | INDOLE, INDAZOLE, BENZOTRIAZOLE AND BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2001-01-30 | — | — | US | disclosed |
| EP-0997474-A1 | Antithrombotic agents | PFIZER INC. (US) | 2000-05-03 | — | — | EP | disclosed |