Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7930449 | 0.80 | MAPT (0.41) | ALDH1A1RAB9AL3MBTL1MAPK1LMNA | |
| SCHEMBL4733265 | 0.77 | CNR2 (0.46) | ALDH1A1RAB9AL3MBTL1NPC1LMNA | |
| SCHEMBL23998421 | 0.73 | PIK3CG (0.47) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL2972209 | 0.73 | ADORA3 (0.47) | ALDH1A1RAB9AL3MBTL1ADORA3ADORA2A | |
| SCHEMBL29383895 | 0.73 | PIK3CG (0.47) | ALDH1A1L3MBTL1ADORA3ADORA2AADORA1 | |
| SCHEMBL1269767 | 0.73 | RAB9A (0.60) | ALDH1A1RAB9AL3MBTL1NPC1MAPK1 | |
| SCHEMBL18658437 | 0.72 | ADORA3 (0.54) | L3MBTL1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24254975 | 0.72 | ADORA3 (0.44) | L3MBTL1ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL9753194 | 0.72 | SORT1 (0.53) | ALDH1A1RAB9AL3MBTL1ADORA3ADORA2A | |
| SCHEMBL358579 | 0.71 | L3MBTL1 (0.53) | RAB9AL3MBTL1PIK3CGNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530524-B1 | Method of producing 2-amino-3-nitro-5-halogenopyridine | ICHIKAWA GOSEI KAGAKU KK (JP) | 2003-02-05 | — | — | EP | disclosed |
| US-5453512-A | Bromination of acylaminopyridine with 2-acylaminopyridinium hydorbromide | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1995-09-26 | — | — | US | disclosed |
| US-5290943-A | Halogenation of pyridine compound | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0530524-A1 | Method of producing 2-amino-3-nitro-5-halogenopyridine | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |