Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787266 | 0.98 | LMNA (0.62) | LMNAMTNR1AMTNR1BMAOAPTGS1 | |
| SCHEMBL15866588 | 0.98 | LMNA (0.62) | LMNAMTNR1AMTNR1BMAOAPTGS1 | |
| SCHEMBL31032939 | 0.98 | LMNA (0.62) | LMNAMTNR1AMTNR1BMAOAPTGS1 | |
| SCHEMBL7042806 | 0.87 | MAPT (0.58) | LMNAMTNR1AMTNR1BMAOAPPARG | |
| SCHEMBL8667454 | 0.87 | MAPT (0.58) | LMNAMTNR1AMTNR1BMAOAPPARG | |
| SCHEMBL17359965 | 0.85 | MTNR1A (0.62) | LMNAMTNR1AMTNR1BMAOAPTGS1 | |
| SCHEMBL4407070 | 0.85 | MTNR1A (0.62) | LMNAMTNR1AMTNR1BMAOAPTGS1 | |
| SCHEMBL11884564 | 0.84 | ABCB1 (0.62) | LMNAPPARGPPARA | |
| SCHEMBL14273066 | 0.83 | L3MBTL1 (0.53) | LMNAMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL10612565 | 0.83 | LMNA (0.58) | LMNAMTNR1AMTNR1BMAOAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997453-B1 | Phenoxyisobutyric acid ammonium salts and pharmaceutical formulations containing them | FATRO SPA (IT) | 2003-02-05 | — | — | EP | disclosed |
| EP-0997453-A1 | Phenoxyisobutyric acid ammonium salts and pharmaceutical formulations containing them | FATRO S.p.A. (IT) | 2000-05-03 | — | — | EP | disclosed |