SCHEMBL787266

SCHEMBL787266

CC(COc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.62
MTNR1A P48039 3/20 0.59
MTNR1B P49286 3/20 0.59
MAOA P21397 1/20 0.52
PTGS1 P23219 1/20 0.52
ADRB2 P07550 1/20 0.50
ADRB1 P08588 1/20 0.50
CYP2D6 P10635 1/20 0.50
ADRB3 P13945 1/20 0.50
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
ALOX15 P16050 1/20 0.50
FFAR1 O14842 1/20 0.46
SCN4A P35499 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15866588 1.00 LMNA (0.62) LMNAMTNR1AMTNR1BMAOAPTGS1
SCHEMBL31032939 1.00 LMNA (0.62) LMNAMTNR1AMTNR1BMAOAPTGS1
Ammonia Solution, Strong SCHEMBL7026341 0.98 LMNA (0.60) LMNAMTNR1AMTNR1BMAOAPTGS1
SCHEMBL7042806 0.89 MAPT (0.58) LMNAMTNR1AMTNR1BMAOAPPARG
SCHEMBL8667454 0.89 MAPT (0.58) LMNAMTNR1AMTNR1BMAOAPPARG
SCHEMBL4407070 0.86 MTNR1A (0.62) LMNAMTNR1AMTNR1BMAOAPTGS1
SCHEMBL17359965 0.86 MTNR1A (0.62) LMNAMTNR1AMTNR1BMAOAPTGS1
SCHEMBL11884564 0.86 ABCB1 (0.62) LMNAPPARGPPARA
SCHEMBL14273066 0.85 L3MBTL1 (0.53) LMNAMTNR1AMTNR1BPPARGPPARA
SCHEMBL10612565 0.85 LMNA (0.58) LMNAMTNR1AMTNR1BMAOAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
EP-4602141-A1 A FRAGRANCE MIXTURE (VI) Symrise AG (DE) 2025-08-20 EP claimed
EP-4532646-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-04-09 EP claimed
US-20250099349-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2025-03-27 US claimed
EP-4519403-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-03-12 EP claimed
CN-116056706-B Biaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof 株式会社LG化学 2024-12-27 CN claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 EP claimed
EP-4473079-A1 A FRAGRANCE MIXTURE Symrise AG (DE) 2024-12-11 EP claimed
US-20240358611-A1 COMPOSITIONS SYMRISE AG (DE) 2024-10-31 US claimed
EP-4429465-A1 COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS Symrise AG (DE) 2024-09-18 EP claimed
EP-1217884-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS Woody Plant Biotech APS (DK) 2002-07-03 EP claimed
WO-2002006215-A1 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES PHARMACIA ITALIA S.P.A. (IT) 2002-01-24 WO claimed
WO-2001020972-A1 METHOD FOR MATURATION OF CONIFER SOMATIC EMBRYOS WOODY PLANT BIOTECH APS (DK) 2001-03-29 WO claimed
EP-0997453-A1 Phenoxyisobutyric acid ammonium salts and pharmaceutical formulations containing them FATRO S.p.A. (IT) 2000-05-03 EP claimed
EP-0621255-B1 Substituted phenoxy-isobutyric acids and esters ADIR (FR) 1997-08-20 EP claimed
US-5627205-A ANTILIPEMIC AGENTS AND ANTIOXIDANTS ADIR ET COMPAGNIE (FR) 1997-05-06 US claimed
US-5512595-A FOR SUPPRESSION OF MEMBRANE LIPID PEROXIDATION, ANTILIPEMIC AGENTS ADIR ET COMPAGNIE (FR) 1996-04-30 US claimed
EP-0002151-B1 PROCESS FOR THE SYNTHESIS OF ESTERS OF PARACHLOROBENZOYL-PHENOXY-ISOBUTYRIC ACID LABORATOIRES FOURNIER S.A. (FR) 1983-05-25 EP claimed
US-4372954-A LOWERING FIBRINOGEN, ANTICOAGULANTS MOREAU PIERRE D (FR) 1983-02-08 US claimed
WO-1981002295-A1 PHENOXYISOBUTYRATES OF MOROXYDIN AND DRUGS CONTAINING THEM MOREAU P 1981-08-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358611-A1 COMPOSITIONS AZI2, NISCH, CIP2A LMNA 4006/4885MTNR1A 1868/4885MTNR1B 2115/4885
US-20250099349-A1 A FRAGRANCE MIXTURE PTMS, EP300, TRPA1 LMNA 2276/4885MTNR1A 2224/4885MTNR1B 3145/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 LMNA 4181/4885MTNR1A 899/4885MTNR1B 823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.