Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023279 | 0.86 | FDPS (0.35) | MMP1MMP2CA1CA2CA12 | |
| SCHEMBL7774946 | 0.83 | CA1 (0.42) | CA1CA2 | |
| SCHEMBL5146947 | 0.75 | MMP1 (0.35) | MMP1MMP2CA1CA2CA12 | |
| SCHEMBL16223469 | 0.72 | CA12 (0.37) | MMP1MMP2CA1CA2CA12 | |
| SCHEMBL16223471 | 0.72 | CA12 (0.37) | MMP1MMP2CA1CA2CA12 | |
| SCHEMBL23641598 | 0.71 | — | — | |
| SCHEMBL11681673 | 0.71 | USP2 (0.39) | MMP1MMP2CA1CA2CA12 | |
| SCHEMBL1966777 | 0.70 | PGK1 (0.39) | MMP1MMP2CA1CA2CA12 | |
| SCHEMBL27738052 | 0.70 | MMP1 (0.38) | MMP1MMP2CA1CA2CA12 | |
| Diethylamine SCHEMBL27831407 | 0.68 | USP2 (0.38) | MMP1MMP2CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117669-B1 | ANTIVIRAL PURINE DERIVATIVES | UNIV CARDIFF (GB) | 2003-01-29 | — | — | EP | disclosed |
| EP-1117669-A1 | ANTIVIRAL PURINE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018775-A1 | ANTIVIRAL PURINE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |