Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027694 | 0.96 | SMN1; SMN2 (0.41) | ZDHHC2SMN1; SMN2PRTN3HDAC3ELANE | |
| SCHEMBL7026588 | 0.91 | PGR (0.41) | SMN1; SMN2PRTN3ELANEBTN3A1 | |
| SCHEMBL7022520 | 0.84 | NPC1 (0.38) | SMN1; SMN2PRTN3 | |
| SCHEMBL7024859 | 0.83 | FAAH (0.39) | SMN1; SMN2 | |
| SCHEMBL3970115 | 0.82 | TSHR (0.39) | PRTN3HDAC3ELANEBTN3A1 | |
| SCHEMBL3970116 | 0.82 | TSHR (0.39) | PRTN3HDAC3ELANEBTN3A1 | |
| SCHEMBL15721086 | 0.81 | KMT2A (0.44) | PRTN3ELANE | |
| SCHEMBL7027815 | 0.80 | PRTN3 (0.39) | PRTN3ELANEBTN3A1 | |
| SCHEMBL5857844 | 0.79 | ELANE (0.40) | PRTN3ELANEBTN3A1 | |
| SCHEMBL873273 | 0.79 | BTN3A1 (0.41) | PRTN3ELANEBTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117669-B1 | ANTIVIRAL PURINE DERIVATIVES | UNIV CARDIFF (GB) | 2003-01-29 | — | — | EP | disclosed |
| EP-1117669-A1 | ANTIVIRAL PURINE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018775-A1 | ANTIVIRAL PURINE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |