Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29642661 | 0.82 | MAOA (0.54) | AHRMAOAMAOBCA12CA2 | |
| SCHEMBL6287157 | 0.82 | MAOA (0.54) | AHRMAOAMAOBCA12CA2 | |
| SCHEMBL3754190 | 0.81 | PTGS2 (0.51) | ALDH2ALDH3A1MAOAMAOBCA12 | |
| SCHEMBL30749724 | 0.81 | PTGS2 (0.51) | ALDH2ALDH3A1MAOAMAOBCA12 | |
| SCHEMBL752211 | 0.77 | ALDH2 (0.41) | SRD5A1ALDH2ALDH3A1MAOBKDM4E | |
| SCHEMBL32672830 | 0.77 | ALDH2 (0.41) | SRD5A1ALDH2ALDH3A1MAOBKDM4E | |
| SCHEMBL5859179 | 0.77 | ALDH2 (0.41) | ALDH2ALDH3A1MAOAMAOBKDM4E | |
| SCHEMBL4596158 | 0.77 | AHR (0.43) | AHRSRD5A1ALDH2ALDH3A1SRD5A2 | |
| SCHEMBL3504905 | 0.77 | ALDH2 (0.47) | SRD5A1ALDH2ALDH3A1CA12CA9 | |
| SCHEMBL1854415 | 0.77 | HSD17B10 (0.48) | ALDH2ALDH3A1MAOBCA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396258-B | Dihydrocoumarin method for synthesizing compound | 河南中烟工业有限责任公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-102161653-A | Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof | ABBOTT LAB | 2011-08-24 | — | — | CN | disclosed |
| EP-1026150-B1 | (2-oxy substituted)-phenylalkanamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 2011-06-29 | — | — | EP | disclosed |
| CN-101443327-A | Chromanylurea compounds that inhibit vanilloid receptor subtype 1(VR1) receptor and uses thereof | ABBOTT LAB (US) | 2009-05-27 | — | — | CN | disclosed |
| US-20070249578-A1 | New amidino derivatives and their use as thrombin inhibitors | ASTRAZENECA AB (SE) | 2007-10-25 | — | — | US | disclosed |
| US-7241757-B2 | Amidino derivatives and their use as thrombin inhibitors | ASTRAZENECA AB (SE) | 2007-07-10 | — | — | US | disclosed |
| EP-1369490-B1 | Method of preparing a composition containing hygromycin A and epi-hygromycin | PFIZER PROD INC (US) | 2006-02-08 | — | — | EP | disclosed |
| EP-1012140-B1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2004-09-29 | — | — | EP | disclosed |
| US-20040186090-A1 | New amidino derivatives and their use as thrombin inhibitors | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | US | disclosed |
| US-6750243-B1 | COMPETITIVE INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASES, ESPECIALLY THROMBIN; chemical synthesis; anticoagulants; treatment of thrombosis | AstraZeneća AB (SE) | 2004-06-15 | — | — | US | disclosed |
| US-6265397-B1 | Amidino derivatives and their use as thrombin inhibitors | ASTRAZENECA AB (SE) | 2001-07-24 | — | — | US | disclosed |
| EP-1075483-A2 | HYGROMYCIN A DERIVATIVES | Pfizer Products Inc. (US) | 2001-02-14 | — | — | EP | disclosed |
| EP-1026150-A1 | (2-oxy substituted)-phenylalkanamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-1012140-A1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | AstraZeneca AB (SE) | 2000-06-28 | — | — | EP | disclosed |
| WO-2000035869-A1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2000-06-22 | — | — | WO | disclosed |
| WO-1999057125-A2 | HYGROMYCIN A DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-11-11 | — | — | WO | disclosed |
| WO-1998057932-A1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRA AKTIEBOLAG (SE) | 1998-12-23 | — | — | WO | disclosed |
| EP-0246114-B1 | PHOTOCHROMIC SPIROPYRAN COMPOUNDS | GEC-MARCONI LIMITED (GB) | 1992-09-02 | — | — | EP | disclosed |
| US-4826977-A | Photochromic spiropyran compounds | THE PLESSEY COMPANY PLC (GB) | 1989-05-02 | — | — | US | disclosed |
| EP-0246114-A2 | Photochromic spiropyran compounds | GEC-MARCONI LIMITED (GB) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249578-A1 | New amidino derivatives and their use as thrombin inhibitors | SERPINC1, SERPINE1, TFPI | AHR 2970/4885SRD5A1 1227/4885ALDH2 4875/4885 |
| US-20040186090-A1 | New amidino derivatives and their use as thrombin inhibitors | SERPINC1, SERPINE1, SERPINB1 | AHR 4130/4885SRD5A1 704/4885ALDH2 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.