SCHEMBL70274

SCHEMBL70274

OCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
MKNK1 Q9BUB5 1/20 0.59
MKNK2 Q9HBH9 1/20 0.59
TAAR1 Q96RJ0 2/20 0.56
HTT P42858 2/20 0.56
ABCC4 O15439 1/20 0.56
LMNA P02545 1/20 0.56
GAA P10253 1/20 0.56
PTGS1 P23219 1/20 0.56
LTA4H P09960 1/20 0.56
FFAR1 O14842 1/20 0.52
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
ALDH1A1 P00352 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
FYN P06241 2/20 0.46
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11274656 1.00 TSHR (0.68) TSHRMKNK1MKNK2TAAR1HTT
Biphenyl SCHEMBL27280595 1.00 TSHR (0.68) TSHRMKNK1MKNK2TAAR1HTT
SCHEMBL15043308 0.93 TSHR (0.59) TSHRMKNK1MKNK2TAAR1HTT
Biphenyl SCHEMBL3279732 0.92 TSHR (0.82) TSHRMKNK1MKNK2TAAR1HTT
SCHEMBL35773 0.90 TSHR (0.62) TSHRMKNK1MKNK2TAAR1HTT
SCHEMBL679970 0.88 MKNK1 (0.56) TSHRMKNK1MKNK2HTTABCC4
SCHEMBL11310791 0.88 MKNK1 (0.56) TSHRMKNK1MKNK2HTTABCC4
SCHEMBL10610530 0.87 TSHR (0.52) TSHRMKNK1MKNK2TAAR1HTT
SCHEMBL21993468 0.87 LTA4H (0.80) TSHRMKNK1MKNK2TAAR1HTT
SCHEMBL12191267 0.87 TSHR (0.52) TSHRMKNK1MKNK2TAAR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1080 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081969-A VSe-Cu2-xSe nanosheet catalysis C (sp)3) -H bond CO2Method for directionally synthesizing alpha-hydroxy/amino acid by carboxylation 2026-05-26 CN claimed
US-12612479-B2 Cross-linkable compositions having a low viscosity for coatings and materials with a high refractive index and a high heat deflection temperature ARKEMA FRANCE (FR) 2026-04-28 US claimed
CN-117005198-B Short carbon chain fluorine-containing finishing agent and preparation and application thereof 德雄实业(浙江)有限公司 2025-04-08 CN claimed
CN-119661322-A Synthesis method of 4-diphenyl methanol 河北科技大学 2025-03-21 CN claimed
CN-116063153-B Synthesis method of 4-diphenyl methanol 中国科学院大连化学物理研究所 2025-03-14 CN claimed
CN-119487102-A Apparatus and efficient method for producing polylactic acid using lactide obtained from devolatilization of polylactic acid 苏尔寿管理有限公司 2025-02-18 CN claimed
EP-4496827-A1 A PLANT AND AN EFFICIENT PROCESS FOR PRODUCING POLYLACTIC ACID USING LACTIDE OBTAINED FROM POLYLACTIC ACID DEVOLATILIZATION Sulzer Management AG (CH) 2025-01-29 EP claimed
EP-4496828-A1 A PLANT AND AN EFFICIENT PROCESS FOR PRODUCING POLYLACTIC ACID Sulzer Management AG (CH) 2025-01-29 EP claimed
CN-119137185-A Oligomeric binaphthyl compounds and thermoplastic resins 三菱瓦斯化学株式会社 2024-12-13 CN claimed
EP-3778722-B1 POLYCARBONATE RESIN COMPOSITION PELLET, PELLET PRODUCTION METHOD AND MOLDED ACTICLE THEREOF MITSUBISHI ENG PLASTICS CORP (JP) 2024-12-11 EP claimed
US-20020165232-A1 Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity SIKORSKI JAMES A (US) 2002-11-07 US claimed
US-20020068736-A1 Biphenyl compounds and their use as oestrogenic agents LESUISSE DOMINIQUE (FR) 2002-06-06 US claimed
US-6288126-B1 Biphenyl compounds and use thereof as oestrogenic agents AVENTIS PHARMA S.A. 2001-09-11 US claimed
EP-1115693-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL $i(TERTIARY)-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY Monsanto Company (US) 2001-07-18 EP claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
EP-0877607-A1 BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS HOECHST MARION ROUSSEL (FR) 1998-11-18 EP claimed
WO-1997027846-A1 BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS HOECHST MARION ROUSSEL (FR) 1997-08-07 WO claimed
US-5043312-A Mixture of imino and isocyanate compounds, biphenyl alcohol in binder on support; image preservation, heat responsiveness MITSUBISHI PAPER MILLS LIMITED (JP) 1991-08-27 US claimed
US-4613622-A Sebosuppressive preparations containing benzyl alcohol derivatives HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-09-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068736-A1 Biphenyl compounds and their use as oestrogenic agents ESR2, ESR1, CYP19A1 TSHR 451/4885MKNK1 4331/4885MKNK2 3885/4885
US-20020165231-A1 Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity CETP, LCAT, MTTP TSHR 4233/4885MKNK1 3426/4885MKNK2 3720/4885
US-12612479-B2 Cross-linkable compositions having a low viscosity for coatings and materials with a high refractive index and a high heat deflection temperature MACF1, HTR3D, CD40 TSHR 1777/4885MKNK1 2001/4885MKNK2 1921/4885
US-20020165232-A1 Substituted N, N-disubstituted cycloalkyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity CETP, DBI, PLTP TSHR 4329/4885MKNK1 3247/4885MKNK2 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.