Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702491 | 0.86 | CES1 (0.47) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL249552 | 0.82 | KMT2A (0.71) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL31175932 | 0.82 | KMT2A (0.71) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9914806 | 0.81 | ERN1 (0.45) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL31588841 | 0.79 | KMT2A (0.67) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL976750 | 0.79 | LMNA (0.52) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL28568883 | 0.79 | TRIM24 (0.54) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL1974950 | 0.77 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL31134296 | 0.77 | ALDH1A1 (0.43) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL548462 | 0.76 | MEN1 (0.48) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807481-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2018-06-20 | — | — | EP | disclosed |
| EP-1807481-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2018-06-20 | — | — | EP | disclosed |
| EP-1859005-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-04-27 | — | — | EP | disclosed |
| EP-1859005-B1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-04-27 | — | — | EP | disclosed |
| US-8940407-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-8940407-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-8940407-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8124249-B2 | Derivatives of fused aromatic systems; stability; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers | MERCK PATENT GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090072712-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090072712-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090072712-A1 | Organic Electroluminescent Device | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-17 | — | — | US | disclosed |
| EP-1859005-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |
| EP-1807481-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Merck Patent GmbH (DE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006097208-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2006-09-21 | — | — | WO | disclosed |
| WO-2006048268-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171225-A1 | Novel Materials For Organic Electroluminescent Devices | OR10J3, EML4, TYR | LMNA 3108/4885KMT2A 2174/4885MEN1 3497/4885 |
| US-20090072712-A1 | Organic Electroluminescent Device | MAL2, ELAVL1, ELAVL3 | LMNA 3781/4885KMT2A 1899/4885MEN1 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.