SCHEMBL7028002

SCHEMBL7028002

COc1ccc(C=CC(=O)C(=O)O)cc1OC

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.76
KDM4E B2RXH2 2/20 0.76
ALDH1A1 P00352 2/20 0.76
HPGD P15428 1/20 0.76
ALOX15 P16050 1/20 0.76
MAPK1 P28482 1/20 0.76
HSD17B10 Q99714 1/20 0.76
NFE2L2 Q16236 1/20 0.69
KMT2A Q03164 4/20 0.67
ABCG2 Q9UNQ0 2/20 0.67
MEN1 O00255 2/20 0.67
IKBKB O14920 2/20 0.63
CHUK O15111 2/20 0.63
IKBKG Q9Y6K9 2/20 0.63
GLO1 Q04760 2/20 0.63
NPC1 O15118 1/20 0.61
STAT1 P42224 1/20 0.61
RAB9A P51151 1/20 0.61
TNFRSF1A P19438 1/20 0.60
SNCA P37840 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7028001 1.00 SMN1; SMN2 (0.76) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
O,O'-Dimethylcaffeic Acid SCHEMBL81317 0.86 KDM4E (1.00) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
O,O'-Dimethylcaffeic Acid SCHEMBL29636389 0.86 KDM4E (1.00) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
O,O'-Dimethylcaffeic Acid SCHEMBL81318 0.86 KDM4E (1.00) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
SCHEMBL9972294 0.86 SMN1; SMN2 (0.69) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
O,O'-Dimethylcaffeic Acid SCHEMBL28025225 0.85 KDM4E (0.97) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
O,O'-Dimethylcaffeic Acid SCHEMBL27858762 0.85 KDM4E (0.97) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
O,O'-Dimethylcaffeic Acid SCHEMBL27858763 0.85 KDM4E (0.97) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
SCHEMBL16621556 0.84 JUN (0.80) SMN1; SMN2KDM4EALDH1A1HPGDALOX15
SCHEMBL30493821 0.84 NFKB1 (0.79) SMN1; SMN2KDM4EALDH1A1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4585266-A2 COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT Korea Research Institute of Chemical Technology (KR) 2025-07-16 EP disclosed
EP-3882244-B1 COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT KOREA RES INST CHEMICAL TECH (KR) 2025-03-05 EP disclosed
EP-3882244-A1 COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT Korea Research Institute of Chemical Technology (KR) 2021-09-22 EP disclosed
EP-2933254-B1 NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT KOREA RES INST CHEMICAL TECH (KR) 2021-01-20 EP disclosed
US-9951058-B2 Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R & D (BE) 2018-04-24 US disclosed
US-9790197-B2 Compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and pharmaceutical composition for prevention or treatment of viral diseases containing same as active ingredient KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R & D (BE) 2017-10-17 US disclosed
US-20170158684-A1 NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2017-06-08 US disclosed
US-20150336920-A1 NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2015-11-26 US disclosed
EP-2933254-A1 NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT Korea Research Institute of Chemical Technology (KR) 2015-10-21 EP disclosed
EP-0889884-B1 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION ALTEON INC (US) 2003-01-29 EP disclosed
US-6380192-B1 FOR INHIBITING NONENZYMATIC CROSS-LINKING (PROTEIN AGING) ALTEON, INC. 2002-04-30 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
US-6060470-A Triazine compounds and methods of use therefor ALTEON, INC. 2000-05-09 US disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-5932578-A CAPABLE OF INHIBITING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS OF TARGET PROTEINS. FOOD SPOILAGE AND ANIMAL PROTEIN AGING CAN BE TREATED. ALTEON INC. (US) 1999-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170158684-A1 NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT RNASE1, HTRA1, IAPP SMN1; SMN2 7/4885KDM4E 4532/4885ALDH1A1 2687/4885
US-20150336920-A1 NOVEL COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT OR OPTICAL ISOMER THEREOF, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF VIRAL DISEASES CONTAINING SAME AS ACTIVE INGREDIENT RNASE1, HTRA1, IAPP SMN1; SMN2 7/4885KDM4E 4532/4885ALDH1A1 2687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.