Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 14/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013367 | 0.71 | ADRA2A (0.40) | LMNA | |
| SCHEMBL21028439 | 0.69 | FDPS (0.45) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL27364236 | 0.69 | CYP4F2 (0.34) | — | |
| SCHEMBL10341436 | 0.69 | FDPS (0.45) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL9435840 | 0.69 | FDPS (0.45) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL10341390 | 0.69 | FDPS (0.41) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL9013011 | 0.69 | ALDH1A1 (0.40) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL23864907 | 0.68 | — | — | |
| SCHEMBL10341385 | 0.67 | FDPS (0.47) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8745062 | 0.65 | FDPS (0.48) | FDPSPDE3ALMNAADRB3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995012600-A1 | CONDENSED DIBENZOXAZEPINES OR DIBENZOTHIAZEPINES USEFUL AS PROSTAGLANDIN-E2 ANTAGONISTS | G. D. SEARLE & CO. (US) | 1995-05-11 | — | — | WO | claimed |
| US-20030004140-A1 | Methods for modulating cell-adhesion mediated drug resistance | NATIONAL INSTITUTES OF HEALTH | 2003-01-02 | — | — | US | disclosed |
| WO-2001064207-A2 | METHODS OF MODULATING CELL-ADHESION MEDIATED DRUG RESISTANCE | UNIVERSITY OF SOUTH FLORIDA (US) | 2001-09-07 | — | — | WO | disclosed |
| EP-0651757-B1 | NOVEL ACYCLIC AMIDINE-GROUP-CONTAINING DIPHOSPHONIC ACID DERIVATIVES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-29 | — | — | EP | disclosed |
| US-5543561-A | CALCIUM METABOLISM DISTURBANCES | BOEHRINGER MANNHEIM GMBH (DE) | 1996-08-06 | — | — | US | disclosed |
| EP-0651757-A1 | NOVEL ACYCLIC AMIDINE-GROUP-CONTAINING DIPHOSPHONIC ACID DERIVATIVES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THESE COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994002492-A1 | NOVEL ACYCLIC AMIDINE-GROUP-CONTAINING DIPHOSPHONIC ACID DERIVATIVES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-03 | — | — | WO | disclosed |