Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30098373 | 0.85 | GPR35 (0.56) | ERN1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL591200 | 0.85 | GPR35 (0.56) | ERN1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL11067071 | 0.85 | GPR35 (0.62) | ERN1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL4301550 | 0.85 | MEN1 (0.52) | ERN1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL207052 | 0.84 | ERN1 (0.50) | ERN1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL205671 | 0.84 | TTR (0.50) | ERN1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL29858635 | 0.84 | TTR (0.50) | ERN1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL2310798 | 0.84 | TDP1 (0.48) | ERN1CRHBPCRHR2PDGFRBFGFR1 | |
| SCHEMBL1734996 | 0.84 | TDP1 (0.45) | ERN1PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL7025831 | 0.83 | PDGFRB (0.47) | ERN1CRHBPCRHR2PDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608233-B2 | Nitrating a bis(4-hydroxyphenyl) bonded to each other or through an electron-donating bridging group, sulfoxide, sulfone or carbonyl group using nitric acid in a solvent and free from other acids | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030055288-A1 | Process for producting bis(4-hydroxy-3-nitrophenyl) compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1277727-A1 | PROCESS FOR PRODUCING BIS(4-HYDROXY-3-NITROPHENYL) COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055288-A1 | Process for producting bis(4-hydroxy-3-nitrophenyl) compound | NOS3, NOS2, NOS1 | ERN1 2828/4885CRHBP 3061/4885CRHR2 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.