SCHEMBL7028752

SCHEMBL7028752

CCOC(=O)COc1c(C)cc(Br)cc1C

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
CYP1A2 P05177 2/20 0.58
CYP2C19 P33261 1/20 0.58
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
KDM4E B2RXH2 2/20 0.47
CYP2D6 P10635 1/20 0.47
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GAA P10253 3/20 0.44
NPSR1 Q6W5P4 1/20 0.44
NLRP3 Q96P20 2/20 0.43
TSHR P16473 2/20 0.42
HSD17B10 Q99714 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7394140 0.86 NLRP3 (0.57) ALDH1A1CYP1A2CYP2C19KDM4EGAA
SCHEMBL29485565 0.86 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C19KDM4ESMN1; SMN2
SCHEMBL15516697 0.84 KMT2A (0.56) ALDH1A1CYP1A2CYP2C19MEN1KMT2A
SCHEMBL7386523 0.83 ATM (0.47) ALDH1A1CYP1A2CYP2C19KDM4ESMN1; SMN2
SCHEMBL4853186 0.83 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C19KDM4ESMN1; SMN2
SCHEMBL1004367 0.82 ALDH1A1 (0.78) ALDH1A1CYP1A2CYP2C19MEN1KMT2A
SCHEMBL16333790 0.82 CYP1A2 (0.54) ALDH1A1CYP1A2CYP2C19MEN1KMT2A
SCHEMBL8194998 0.81 CD69 (0.46) ALDH1A1CYP1A2CYP2C19KDM4EGAA
SCHEMBL27602765 0.81 NLRP3 (0.45) ALDH1A1CYP1A2CYP2C19KDM4EGAA
SCHEMBL13858739 0.81 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP2C19KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025122555-A1 S1P 1 RECEPTOR AGONISTS AND USES THEREOF VALO HEALTH, INC. (US) 2025-06-12 WO disclosed
CN-100418944-C Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof KISSEI PHARMACEUTICAL (JP) 2008-09-17 CN disclosed
CN-1751019-A Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof KISSEI PHARMACEUTICAL (JP) 2006-03-22 CN disclosed
EP-0758243-B1 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa TEXAS BIOTECHNOLOGY CORP (US) 2003-03-12 EP disclosed
EP-0758243-A4 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa TEXAS BIOTECHNOLOGY CORP (US) 1997-08-20 EP disclosed
EP-0758243-A1 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWISa TEXAS BIOTECHNOLOGY CORPORATION (US) 1997-02-19 EP disclosed
WO-1995029682-A1 BINDING OF E-SELECTIN, P-SELECTIN OR L-SELECTIN TO SIALYL-LEWISx OR SIALYL-LEWIS?a¿ TEXAS BIOTECHNOLOGY CORPORATION (US) 1995-11-09 WO disclosed