Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29485565 | 0.89 | ALDH1A1 (0.47) | NLRP3L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12769529 | 0.87 | NLRP3 (0.49) | NLRP3TDP1ATML3MBTL1MAPT | |
| SCHEMBL7386523 | 0.86 | ATM (0.47) | NLRP3ATML3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL4853186 | 0.86 | ALDH1A1 (0.45) | NLRP3TDP1L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL7028752 | 0.86 | ALDH1A1 (0.58) | NLRP3L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL13858739 | 0.84 | ALDH1A1 (0.53) | NLRP3L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL27602765 | 0.84 | NLRP3 (0.45) | NLRP3L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8194998 | 0.84 | CD69 (0.46) | NLRP3L3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15516922 | 0.83 | MMP1 (0.48) | L3MBTL1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7391047 | 0.83 | ALDH1A1 (0.43) | NLRP3TDP1ATML3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905068-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1999-05-18 | — | — | US | disclosed |