Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11354192 | 0.94 | TBK1 (0.37) | TBK1HSD17B10KMT2AIKBKEKDM4E | |
| SCHEMBL11367261 | 0.79 | NT5E (0.45) | KCNH2HSD17B10KMT2ACSNK2BCSNK2A1 | |
| SCHEMBL6206386 | 0.78 | TBK1 (0.51) | TBK1IKBKEKDM4E | |
| SCHEMBL29674734 | 0.78 | TBK1 (0.51) | TBK1IKBKEKDM4E | |
| SCHEMBL11375422 | 0.77 | GPR35 (0.46) | KCNH2HSD17B10KMT2APIM1CDC7 | |
| SCHEMBL11375110 | 0.76 | TBK1 (0.48) | TBK1KMT2AIKBKEKDM4ESMN1; SMN2 | |
| SCHEMBL11107442 | 0.76 | TBK1 (0.51) | TBK1HSD17B10KMT2ACSNK2BCSNK2A1 | |
| SCHEMBL2238422 | 0.74 | TBK1 (0.63) | TBK1IKBKEKDM4E | |
| SCHEMBL2907432 | 0.74 | TBK1 (0.56) | TBK1IKBKEKDM4E | |
| SCHEMBL11368425 | 0.74 | TBK1 (0.46) | TBK1IKBKEKDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095011-A4 | NOVEL FLUORESCENT LANTHANIDE CHELATES | SMITHKLINE BEECHAM CORP (US) | 2003-01-08 | — | — | EP | disclosed |
| EP-1095011-A1 | NOVEL FLUORESCENT LANTHANIDE CHELATES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001663-A1 | NOVEL FLUORESCENT LANTHANIDE CHELATES | SMITHKLINE BEECHAM CORPORATION (US) | 2000-01-13 | — | — | WO | disclosed |