SCHEMBL7029446

SCHEMBL7029446

CS(=O)(=O)N(C(=O)c1ccccc1)c1cc(-c2c(C(F)(F)F)n(N)c(=O)[nH]c2=O)c(F)cc1C#N

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 2/20 0.33
BCAT2 O15382 1/20 0.31
BCAT1 P54687 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7027406 0.93 GPBAR1 (0.32) GPBAR1
SCHEMBL7032618 0.91 MAPT (0.34) GPBAR1
SCHEMBL7029976 0.87 AR (0.31)
SCHEMBL7026390 0.81 AR (0.30)
SCHEMBL7028724 0.78 MEN1 (0.34)
SCHEMBL7034134 0.77 MEN1 (0.31)
SCHEMBL7024088 0.76 KMT2A (0.33)
SCHEMBL8565691 0.76 MEN1 (0.33)
SCHEMBL8425512 0.76 TRPV4 (0.35) BCAT2BCAT1
SCHEMBL7030317 0.75 L3MBTL1 (0.38) GPBAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1278413-A2 N-ARYL-URACILE-BASED HERBICIDES Bayer CropScience AG (DE) 2003-01-29 EP disclosed
WO-2001039597-A2 N-ARYL-URACILE-BASED HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-06-07 WO disclosed